en POLSKI
eISSN: 2300-8660
ISSN: 0031-3939
Pediatria Polska - Polish Journal of Paediatrics
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1/2024
vol. 99
 
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abstract:
Case report

Synchronous neoplasms in a paediatric patient

Aleksandra Dembowska
1
,
Maciej Dubaj
1
,
Karol Bigosiński
1
,
Mateusz Raniewicz
1
,
Małgorzata Mitura-Lesiuk
2

  1. Student Scientific Society of the Department of Paediatric Haematology, Oncology, and Transplantology, Medical University of Lublin, Poland
  2. Department of Paediatric Haematology, Oncology, and Transplantology, Medical University of Lublin, Poland
Pediatr Pol 2024; 99 (1): 66-70
Online publish date: 2024/03/05
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Cancer is the second leading cause of death in the paediatric population after injuries. 3–10% of them are multiple primary malignant neoplasms, which are a huge problem both in diagnosis and treatment. We present a case of a boy, nearly 2 years old, with synchronous coexistence of T-cell acute lymphoblastic leukaemia and Langerhans cell histiocytosis. During the M AIEOP BFM ALL 2017 Protocol, the patient suffered an injury to the right elbow joint. Despite the limb being provided with a plaster cast and orthopaedic intervention, local improvement was not achieved. The obtained result of the histopathological examination revealed a disseminated aggressive form of histiocytosis affecting the skeletal system and lungs. In the presence of non-specific symptoms for the diagnosed cancer, one should be vigilant and suspect the coexistence of another proliferative process, which may cause no improvement despite proper therapeutic management.
keywords:

children, acute lymphoblastic leukaemia, synchronous neoplasms, Langerhans-cell histiocytosis